Gastrin and gastrointestinal disease.
نویسندگان
چکیده
منابع مشابه
Gastrin releasing peptide and gastrin releasing peptide receptor expression in gastrointestinal carcinoid tumours.
AIMS To establish whether gastrin releasing peptide (GRP) and the GRP receptor (GRPR) are expressed together in gastrointestinal carcinoid tumours. METHODS Twenty six carcinoid tumours from the stomach, small intestine, appendix, and colorectum were investigated by immunohistochemistry for GRP and GRPR. RESULTS GRP was detected in nine of 19 tumours and GRPR in 22 of 26. Coexpression of bot...
متن کاملGastrin, cholecystokinin and gastrointestinal tract functions in mammals.
The aim of the present review is to synthesise and summarise our recent knowledge on the involvement of cholecystokinin (CCK) and gastrin peptides and their receptors in the control of digestive functions and more generally their role in the field of nutrition in mammals. First, we examined the release of these peptides from the gut, focusing on their molecular forms, the factors regulating the...
متن کاملInteraction of gastrin I and secretin on gastrointestinal circular muscle.
LIPSHUTZ,~ILLIAM, AND SIDNEY COHEN. Interaction of gastrin I and secretin on gastrointestinal circular muscle. Am. J. Physiol. 222(3) : 775-781. 1972.-The effect of gastrin I and secretin was studied on the in vitro circular smooth muscle of the lower esophageal sphincter (LES), antrum, and pylorus of the opossum. Each muscle was studied at its length of optimal tension development, L,, as dete...
متن کاملInteraction between epidermal growth factor and gastrin on DNA synthesis of the gastrointestinal mucosa in rats.
Interaction between epidermal growth factor (EGF) and gastrin on DNA synthesis of the rat gastrointestinal tract was examined. Fasted male rats were divided into four groups and injected with 10 μg/kg human EGF, 300 μg/kg pentagastrin, human EGF plus pentagastrin and saline (control), respectively. The animals were sacrificed 8 or 16 hr thereafter and the incorporation of [H]thymidine into the ...
متن کاملGastrointestinal - Clinical Management Conditions Associated with Increased Gastrin and Secretin secretion
Gastrin Peptide hormone normally produced in antral portion of stomach in response to peptide fragments& amino acids (esp. tryptophan, phenylalanine) released from ingested foods. Physiologic gastrin production is also stimulated by gastric distention via acetylcholine. Gastrin release is inhibited when intragastric pH falls below 3.0. Gastrin stimulates acid production by oxyntic cells and gro...
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ژورنال
عنوان ژورنال: BMJ
سال: 1972
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5835.297